IPA the Fast Path to Toxicity Targets of Interest
Metal-rich particulate matter inhalation exposure results in target organ toxicity but also adverse systemic effects including cardiovascular dysfunction and immunosuppression. As a preliminary search for induction of systemic mechanisms, generation of comprehensive transcriptome datasets by DNA microarray, along with gene network analysis, was performed from circulating whole blood cells, aorta, and lung then compared to determine related biological signaling following inhalation exposure.
Also demonstrated are some exciting new features in the new 2013 IPA Spring Release. Learn how IPA can help you quickly filter down to specific toxicity targets of interest