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The Ingenuity Scientific Seminar series explores in detail how IPA can be used to answer specific scientific questions.
Click on a date below to register and view date in your time zone.
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IPA and Coronary Artery Disease: A Case Study from Harvard
Presented by Dr. Jochen Danny Muehlschlegel, M.D., Harvard Medical School
See how IPA was used for the discovery of novel pathways of affected genes in coronary artery disease. Cardiopulmonary bypass (CPB) with cardioplegic arrest is associated with ischemia leading to metabolic substrate depletion, reperfusion injury, apoptosis and necrosis. The study hypothesized that human left ventricular (LV) myocardium responds differently to the stress of (CPB) depending on the presence or absence of coronary artery disease (CAD). Therefore, they assessed differences in gene expression in patients undergoing aortic valve replacement (AVR) with (CPB) prior to and after cardioplegic arrest using whole-genome transcriptional profiling.
- A Combined Biological and Bioinformatic Analysis of Primary and Metastatic Tissues from NGS Ewing's Sarcoma Patients
- Using IPA to Analyze Illumina RNA-Seq Data Reveals Abundance-Specific Biological Signatures in Alzheimer's Disease
- Utilizing IPA for the Discovery and Development of New Pain Therapeutics
- NGS: Insights into Prostate Cancer Mechanisms via Integrated In Silico RNA-Seq Analysis of NGS Patient Data
- Biomarkers for Prostate Cancer: How IPA Can Help Explore Potential Biomarkers for a Complex Disease
- MicroRNA: Using IPA's microRNA Target Filter to Identify and Prioritize microRNA Targets for Melanoma
- Using IPA to Explore Pathways and Investigate Effects of Insulin Resistance on Human Adipose
- Biomarkers and microRNA: Integrative Analysis of microRNA and mRNA as Biomarkers for Ovarian Cancer
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