Platform

Scalable technology for researchers and clinicians to discover biological insights from genomics data for improving research and clinical decision-making

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QIAGEN’s Ingenuity Platform Consists of Three Main Components

  • Content Acquisition
  • Knowledge Base
  • Applications

All three layers of QIAGEN’s Ingenuity Platform enable researchers and clinicians to answer the most fundamental questions about the biology they are studying.  Access to the Ingenuity Platform is delivered through a secure, private cloud-based service where users upload and analyze their data using the Ingenuity data analysis and interpretation applications.

QIAGEN’s Ingenuity Platform Has Broad Applicability

  • Pharmacogenomics
  • Toxicogenomics
  • Proteomics
  • Drug Target Discovery
  • Biomarker Discovery
  • Metabolomics
  • Personal Genomics
  • Rare Disease
  • And more…

Content Acquisition

The Content Acquisition layer is a robust set of people, processes and technology for curating high-quality scientific relationships from peer-reviewed journals and both public and private biomedical databases.  Information collected goes through a thorough, repeatable quality control process to insure the molecular information, called Findings, are captured as originally published and are integrated into the Ingenuity Ontology, a framework for organizing and describing biological evidence. Both confirmation and contradictory Findings are captured, including the source publication and the context for the Finding, to ensure users will have all the supporting evidence required to assess the applicability of a specific Finding.

Knowledge Base

The challenge with published literature as a resource for genomics data analysis is that it is unstructured and therefore reduces the utility of the information. At Ingenuity we’ve tackled this problem by structuring the fundamental knowledge into ontologies that provide the scaffolding for the Knowledge Base. The Ontology structures the curated content for relevance and computation by the applications.

Applications

The Applications Layer provides a rich set of intuitive web-based applications for quickly analyzing and accurately interpreting the biological meaning in genomics data. The Knowledge Base is used as a starting point for exploration and a bridge between novel discovery and known biology. When accessed through QIAGEN’s Ingenuity Applications, it provides you with a powerful resource for searching relevant and substantiated knowledge from the literature, and for interpreting experimental results in the context of larger biological systems for greater confidence in decision-making.

References: Perspective from Doug Bassett, QIAGEN Redwood City, CSO/CTO. Biological analysis and interpretation for improved research outcomes. Drug Discovery World. Spring 2012.