How can IPA help in toxicity assessment?
IPA is software from Ingenuity® Systems that helps researchers model, analyze, and understand the complex biological and chemical systems at the core of life science research. You can use IPA in toxicology research to:
- Anchor data to histopathology, clinical chemistry, and disease pathology endpoints (steatosis, necrosis, apoptosis, fibrosis, inflammation, etc) and helps researchers understand molecular processes leading to these endpoints
- Deliver detailed mechanistic hypotheses underlying tox-specific phenotypes
- Provide rapid insights into candidate tissue-specific biomarkers through fully integrated IPA biomarker capabilities
- Provide evidence to support/reject hypotheses generated from pre-clinical toxicity assays
- Access important and up-to-date findings from the scientific literature, including information associated with cardiotoxicity, nephrotoxicity, and hepatotoxicity
Inform decisions related to lead compound optimization
- Accelerate the interpretation of toxicogenomics data and the generation of reports summarizing findings from toxicity studies by leveraging pathway content and molecule to phenotype associations
|
