Transcriptomics Analysis of Human Redefines mTOR Role in Growth Regulation
Wednesday, Feb 13th, 3:50 pm – 4:20 pm, Bioinformatics Talk
Presenter: Jamie Timmons, Professor of Systems Biology, Loughborough University
Transcriptomics analysis has evolved to the point that robust experiments can be done in-silico. Using Upstream Regulator Analysis in Ingenuity’s IPA, we aimed to discover new molecular regulators of human muscle aging and growth responses. This tool provides a unique strategy to discover plausible molecular regulators of in vivo disease phenotypes. Evaluation of our clinical data enabled discovery of novel regulatory association between mTOR and human muscle growth.
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