Broad and Timely Content – Ingenuity^® Expert Findings  and our new Ingenuity^® ExpertAssist Findings help you access up-to-date knowledge from a broad range of biomedical journals.  All of Ingenuity’s content is structured to enable powerful computation and manually reviewed to ensure accuracy. Both types of content are now updated weekly.

• In addition to our Ingenuity Expert Findings (detailed biological relationships that are manually curated from the full-text of scientific publications), we now are including new Ingenuity ExpertAssist Findings.  Ingenuity ExpertAssist Findings cover a broader set of biomedical journals and include Findings published as recently as last week, letting you integrate new insights into your IPA workflows.
• Filtering capabilities let you choose which types of content to include in analysis results and hypothesis generation, and lets you refresh Networks and Pathways with recently added Findings.
• Ingenuity ExpertAssist Findings and Ingenuity Expert Findings both undergo manual quality control steps to ensure that all Ingenuity Findings are context-rich, broad, and semantically consistent.

Professional Dynamic Reports

• Pathway, List, and Analysis reports can be saved and shared in PDF format, letting you clearly and consistently communicate insights between team members.
• Dynamic reports let you link back to knowledge in the Ingenuity Knowledge Base.
• Comprehensive, standardized reports overcome the hurdle of translating key insights, pathways, and analysis results from expert IPA users to novice or non-IPA users.
• Analysis results and current hypotheses are versioned for reporting and record keeping.

HMDB ID Support

• Metabolomics data can be uploaded more easily, streamlining the IPA-Metabolomics™ analysis workflow.
• View comprehensive information on metabolites, including expression and localization Findings, by searching for metabolite ChemViews with HMDB identifiers.

Collaboration Work Space

• Easily create a shared workspace for a large group of collaborators within a single research institute or company, or between collaborating institutes.
• Read/write protections provide collaborators with the ability to explore and iterate on analyses, datasets, and custom Lists or Pathways in the workspace, while ensuring that the original files, hypotheses and insights are not overwritten.

New Content

• Seven new disease pathways relating to cancer, rheumatoid arthritis, multiple sclerosis, Alzheimer’s and cardiovascular disease:
  • Breast Cancer Regulation by Stathmin1
  • Glioblastoma Multiforme Signaling
  • Glioma Invasiveness Signaling
  • Neuroprotective Role of THOP1 in Alzheimer's Disease
  • Pathogenesis of multiple sclerosis
  • Role of NFAT in Cardiac Hypertrophy
  • RANK Signaling in Osteoclasts

• Five new signaling pathways relating to cytokine signaling and cellular and humoral immune responses:

• B Cell Development
• Granzyme A Signaling (in Cytotoxic T Lymphocytes)
• Granzyme B Signaling (in Cytotoxic T Lymphocytes)
• IL-1 Signaling
• Regulation of IL-2 Expression in Activated and Anergic T Lymphocytes

• ~30K new Findings covering Schizophrenia and related diseases, cellular and humoral immune responses, and pathogenesis.