Gene-to-Disease Associations:
- Thousands of new gene-to disease associations from OMIM for hundreds of genetic disorders allow you to discover a wider spectrum of diseases related to your genes of interest.
Protein Ubiquitination Content:
- New manually curated protein ubiquitination content allows you to gain a better understanding of molecular mechanisms of protein stability and degradation.
New Immunology Pathways:
- Activation of IRF by Cytosolic Pattern Recognition Receptors
- Caveolar-mediated Endocytosis
- Clathrin-mediated Endocytosis
- Macropinocytosis
- FcγReceptor-mediated Phagocytosis in Macrophages and Monocytes
- IL-8 Signaling
- IL-12 Signaling and Production in Macrophages
- Role of RIG1-like Receptors in Antiviral Innate Immunity
- Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses
- Role of PKR in Interferon Induction and Antiviral Response
- TREM1 Signaling
Host/Pathogen Interactions
- Additional interactions and regulatory events between pathogen and host proteins have been added.
Women’s Health Content:
- Additional content to understand the etiology of reproductive system disorders supports the development of novel therapeutic interventions and the discovery of more effective diagnostic markers of disease.
- Luteinization
- Endometriosis
- Leiomyoma
Additional Clinical Trial Information:
- Drug Views overlaid onto Networks and Pathways helps prioritize existing studies.
- Understand current drug approval status, ongoing clinical trials and their sponsors, and indications being treated.
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