March 17-18, 2014
Monday, March 17th from 2:25 – 2:40 pm
Integrated microRNA and mRNA signature associated with the transition from the locally confined to the metastasized renal cell carcinoma
We analyzed miRNA and mRNA profiles from primary clear cell renal cell carcinomas from patients with or without metastasis. Using Ingenuity Pathway Analysis microRNA Target Filter, we identified novel target genes of dysregulated miRNAs which are involved in the transition from primary RCC without metastases into tumors generating distant metastasis.
Recent research has shown microRNAs to have tremendous potential as non-invasive biomarkers for the diagnosis and prognosis of disease, monitoring of treatment, and patient stratification, with exosome-derived microRNAs of particular interest. Cambridge Healthtech Institute’s Tenth Annual microRNA as Biomarkers and Diagnostics will cover the latest developments in the use of microRNA in the early detection of disease for more effective treatment, monitoring tumor growth and disease progression, issues associated with microRNA measurement, and the potential for personalized medicine based on microRNA profile.
Learn more here.