Join us for our latest webinar presented by Vivien Sheehan, Assistant Professor of Pediatrics at Baylor College of Medicine. Vivien will be speaking about her work in pharmacogenomics.
This presentation will cover sickle cell disease (SCD), specifically the genetic component to fetal hemoglobin response to hydroxyurea. Such knowledge will enhance the ability to predict drug response, improving patient care by allowing selection of individuals who will benefit most from hydroxyurea, and offer alternative therapies.
Attendees will learn:
- How Ingenuity Variant Analysis can be used to analyze variants associated with high or low drug response or drug dosage.
- That the exonically variable criteria found in the confidence filter can be helpful in eliminating genes with a high degree of variability that may result in false associations.
- How burden analysis is a valuable addition to the analysis.
- That the common-variants filter should be used with caution in phenotypes not subject to evolutionary pressure, such as drug response.